Possessing encyclopedia-like intelligence, unusual zookeeper's son Pi Patel sets sail for America, but when the ship sinks, he escapes on a life boat and is lost at sea with a dwindling number of animals until only he and a hungry Bengal tiger remain.

In Lisbon in 1904, a young man named Tomás discovers an old journal. It hints at the existence of an extraordinary artifact that--if he can find it--would redefine history. Traveling in one of Europe's earliest automobiles, he sets out in search of this strange treasure. Thirty-five years later, a Portuguese pathologist devoted to the murder mysteries of Agatha Christie finds himself at the center of a mystery of his own and drawn into the consequences...

A young Pi Patel, overcoming a cataclysmic shipwreck, finds himself stranded on a lifeboat with the last survivor, a ferocious Bengal tiger named Richard Parker.